|
KMID : 1036920230280010010
|
|
Annals of Pediatric Endocrinology & Metabolism
2023 Volume.28 No. 1 p.10 ~ p.19
|
|
|
Vitamin D deficiency is a public health emergency amongst indonesian children and adolescents: a systematic review and meta-analysis of prevalence
|
|
Gilbert Sterling Octavius
Ayesha Shakila
Mariska Meliani
Anita Halim
|
|
|
Abstract
|
|
|
Purpose: This study aimed to describe the prevalence of vitamin D deficiency in Indonesian children and adolescents.
Methods: This was a meta-analysis of prevalence using the Hartung-Knapp-Sidik-Jonkman method with a random effects model. A prediction interval was used to estimate true effects. We searched PubMed, MEDLINE, Cochrane Library, Science Direct, Google Scholar, and 3 Indonesian databases (Indonesian Scientific Journal Database, Neliti, and Indonesia One Search). We included cross-sectional or case-control studies that provided data on the prevalence of vitamin D deficiency. We excluded case reports, case series, cohort studies, or studies outside Indonesia. We computed point prevalence by dividing the number of children with hypovitaminosis D by the total number of subjects in that study. This review was registered with PROSPERO (International Prospective Register of Systematic Reviews) (CRD42022329814).
Results: Of 1,397 manuscripts identified, 7 were included in this review. A total of 5,870 children were included in this meta-analysis, ranging in age from 6 months to 19 years. The prevalence of hypovitaminosis D in Indonesia was calculated as 33% (95% confidence interval [CI], 9?56) and was higher in females (60% [95% CI, 58?62]) than in males (40% [95% CI, 38?42]). Mean serum vitamin D level was 22.74 ng/mL (95% CI, 16.95?30.51) with a prediction interval of 15.96 ng/mL to 29.52 ng/mL.
Conclusion: Vitamin D deficiency is a public health emergency in Indonesia. Strategies to detect and treat vitamin D deficiency in Indonesian children and adolescents should be implemented immediately.
|
|
|
KEYWORD
|
|
|
Hypovitaminosis D, Indonesia, Vitamin D deficiency, Public health emergency, Prevalence
|
|
|
FullTexts / Linksout information
|
|
|
|
|
|
Listed journal information
|
|
  
|
|